End-stage kidney failure is the stage at which patients need to go on dialysis or undergo a kidney transplant to survive. Recent research shows that intensive treatment of hypertension in certain group of people with kidney disease by forcing blood pressure far below the currently recommended threshold may effectively reduce the number of people who lose their kidney function and need dialysis.

There were some exceptions as not everyone in the research was improved by intensive blood pressure treatment. Unlike the patients who had less or no protein in their urine, it was the sicker patients those with protein in their urine, who benefited most from the more intense blood pressure treatment.

Studies say that doctors should check for protein in the urine before determining the blood pressure target for patients with kidney disease. If the patient has protein in the urine, the reduced blood pressure target has the ability to slow down the progression of kidney disease. But if the patient has little or no protein in the urine, the goal of obtaining lower blood pressure is not worth the additional effort, and the standard goal is just as effective. While the study showed that one group with kidney disease benefited from intensive blood pressure therapy, a large percentage of these patients still ended up with end-stage kidney disease.

Journal of Clinical & Experimental Nephrology focuses on the dissemination of the latest advancements on the current knowledge on all the aspects of Nephrology such as Peritoneal Dialysis, Kidney Diseases, Acute Renal Replacement Therapy, Chronic Kidney Disease, End-Stage Renal Diseases, Lupus Nephritis and Renal Transplantation.

Regards,

Calvin Parker
Journal of Clinical & Experimental Nephrology
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